Hydroxymethyl Ivacaftor

• CAT Number: R032903
• CAS Number: 1246213-23-9
• Molecular Formula: C24H28N2O4
• Molecular Weight: 408.49
• Purity: ≥95%
• Synonyms: N-[2-(1,1-Dimethylethyl)-5-hydroxy-4-(2-hydroxy-1,1-dimethylethyl)phenyl]-1,4-dihydro-4-oxo-3-quinolinecarboxamide
• Storage: Store at room temperature
• IUPAC Name: N-[2-tert-butyl-5-hydroxy-4-(1-hydroxy-2-methylpropan-2-yl)phenyl]-4-oxo-1H-quinoline-3-carboxamide
• InChI: InChI=1S/C24H28N2O4/c1-23(2,3)16-10-17(24(4,5)13-27)20(28)11-19(16)26-22(30)15-12-25-18-9-7-6-8-14(18)21(15)29/h6-12,27-28H,13H2,1-5H3,(H,25,29)(H,26,30)
• InChIKey: HFNOECBPRSJRQD-UHFFFAOYSA-N
• SMILES: CC(C)(C)C1=CC(=C(C=C1NC(=O)C2=CNC3=CC=CC=C3C2=O)O)C(C)(C)CO

Hydroxymethyl Ivacaftor（Cat No.:R032903）is a derivative of Ivacaftor, a drug used to treat cystic fibrosis by enhancing the function of the CFTR protein. This modified compound features a hydroxymethyl group, potentially offering improved pharmacokinetic properties. Hydroxymethyl Ivacaftor is significant in pharmaceutical research for studying drug metabolism, efficacy, and safety profiles. Its role in modulating CFTR activity makes it a valuable asset in developing new therapeutic strategies for cystic fibrosis, aiming to enhance patient outcomes and provide deeper insights into drug action mechanisms.