For research use only. Not for therapeutic Use.
Hydroxyzine-d8 Dihydrochloride (Cat No.:C000689) is a deuterium-labeled derivative of hydroxyzine, an antihistamine used to relieve symptoms of allergic reactions and anxiety. The deuterium substitution enhances molecular stability and enables precise isotopic labeling for research purposes. Hydroxyzine works by blocking histamine receptors, reducing allergic responses and anxiety.
| Catalog Number | C000689 |
| CAS Number | 1808202-93-8 |
| Synonyms | 2-[2-[4-[(4-Chlorophenyl)-phenylmethyl]-1-piperazinyl-d8]ethoxy]ethanol Dihydrochloride; Alamon-d8; Atarax-d8; Aterax-d8; Durrax-d8; Orgatrax-d8; Quiess-d8; |
| Molecular Formula | C₂₁H₁₉D₈ClN₂O₂ • 2HCl |
| Purity | ≥95% |
| Solubility | Methanol (Slightly), Water (Slightly) |
| Appearance | White to Off-White Solid |
| Storage | -20°C, Hygroscopic |
| IUPAC Name | 2-[2-[4-[(4-chlorophenyl)-phenylmethyl]-2,2,3,3,5,5,6,6-octadeuteriopiperazin-1-yl]ethoxy]ethanol;dihydrochloride |
| InChI | InChI=1S/C21H27ClN2O2.2ClH/c22-20-8-6-19(7-9-20)21(18-4-2-1-3-5-18)24-12-10-23(11-13-24)14-16-26-17-15-25;;/h1-9,21,25H,10-17H2;2*1H/i10D2,11D2,12D2,13D2;; |
| InChIKey | ANOMHKZSQFYSBR-FLZNRFFQSA-N |
| SMILES | C1CN(CCN1CCOCCO)C(C2=CC=CC=C2)C3=CC=C(C=C3)Cl.Cl.Cl |
| Reference | Goldenthal, E.I., et al.: Toxicol. Appl. Pharmacol., 18, 185 (1971), Tsau, J., et al.: Anal. Profiles Drug Subs., 7, 319 (1978) |
