Hydroxyzine-d8

• CAT Number: S000534
• CAS Number: 1189480-47-4
• Molecular Formula: C21H19D8ClN2O2
• Molecular Weight: 382.95
• Purity: ≥95%
• IUPAC Name: 2-[2-[4-[(4-chlorophenyl)-phenylmethyl]-2,2,3,3,5,5,6,6-octadeuteriopiperazin-1-yl]ethoxy]ethanol
• InChI: InChI=1S/C21H27ClN2O2/c22-20-8-6-19(7-9-20)21(18-4-2-1-3-5-18)24-12-10-23(11-13-24)14-16-26-17-15-25/h1-9,21,25H,10-17H2/i10D2,11D2,12D2,13D2
• InChIKey: ZQDWXGKKHFNSQK-BGKXKQMNSA-N
• SMILES: C1CN(CCN1CCOCCO)C(C2=CC=CC=C2)C3=CC=C(C=C3)Cl

Hydroxyzine-d8（Cat No.:S000534） is a deuterated form of hydroxyzine, where eight hydrogen atoms have been replaced with deuterium. This modification enhances the molecule’s stability and alters its pharmacokinetics, useful for detailed research studies. Hydroxyzine itself is an antihistamine used to treat anxiety, nausea, itching, and allergies. It also has sedative properties. The deuterated version, hydroxyzine-d8, is primarily used in scientific research to understand the drug’s absorption, distribution, metabolism, and excretion processes. This knowledge helps in refining the drug’s usage and improving its efficacy and safety profile in clinical settings.