For research use only. Not for therapeutic Use.
Hygromycin A（Cat No.:I041052）is an aminoglycoside antibiotic derived from Streptomyces hygroscopicus. It is primarily used in laboratory research to select for genetically modified cells, as it inhibits protein synthesis by binding to the ribosome, preventing the elongation of polypeptides. Hygromycin A is effective against a wide range of bacterial, fungal, and yeast species, making it valuable in microbiological studies. It is commonly used in molecular biology to maintain selective pressure in transfected cells, ensuring that only those expressing a resistance gene survive in the presence of the antibiotic.
| CAS Number | 6379-56-2 |
| Synonyms | (E)-N-[(3aS,4R,5R,6S,7R,7aR)-4,6,7-trihydroxy-3a,4,5,6,7,7a-hexahydro-1,3-benzodioxol-5-yl]-3-[4-[(2S,3S,4S,5S)-5-acetyl-3,4-dihydroxyoxolan-2-yl]oxy-3-hydroxyphenyl]-2-methylprop-2-enamide |
| Molecular Formula | C23H29NO12 |
| Purity | ≥95% |
| IUPAC Name | (E)-N-[(3aS,4R,5R,6S,7R,7aR)-4,6,7-trihydroxy-3a,4,5,6,7,7a-hexahydro-1,3-benzodioxol-5-yl]-3-[4-[(2S,3S,4S,5S)-5-acetyl-3,4-dihydroxyoxolan-2-yl]oxy-3-hydroxyphenyl]-2-methylprop-2-enamide |
| InChI | InChI=1S/C23H29NO12/c1-8(22(32)24-13-14(27)16(29)21-20(15(13)28)33-7-34-21)5-10-3-4-12(11(26)6-10)35-23-18(31)17(30)19(36-23)9(2)25/h3-6,13-21,23,26-31H,7H2,1-2H3,(H,24,32)/b8-5+/t13-,14+,15-,16-,17+,18+,19-,20+,21-,23-/m1/s1 |
| InChIKey | YQYJSBFKSSDGFO-IIHALWDASA-N |
| SMILES | C/C(=C\C1=CC(=C(C=C1)O[C@H]2[C@H]([C@@H]([C@H](O2)C(=O)C)O)O)O)/C(=O)N[C@@H]3[C@@H]([C@H]([C@@H]4[C@H]([C@@H]3O)OCO4)O)O |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
