Hygromycin A

• CAT Number: I041052
• CAS Number: 6379-56-2
• Molecular Formula: C23H29NO12
• Molecular Weight: 511.48
• Purity: ≥95%
• Synonyms: (E)-N-[(3aS,4R,5R,6S,7R,7aR)-4,6,7-trihydroxy-3a,4,5,6,7,7a-hexahydro-1,3-benzodioxol-5-yl]-3-[4-[(2S,3S,4S,5S)-5-acetyl-3,4-dihydroxyoxolan-2-yl]oxy-3-hydroxyphenyl]-2-methylprop-2-enamide
• InChI: InChI=1S/C23H29NO12/c1-8(22(32)24-13-14(27)16(29)21-20(15(13)28)33-7-34-21)5-10-3-4-12(11(26)6-10)35-23-18(31)17(30)19(36-23)9(2)25/h3-6,13-21,23,26-31H,7H2,1-2H3,(H,24,32)/b8-5+/t13-,14+,15-,16-,17+,18+,19-,20+,21-,23-/m1/s1
• InChIKey: YQYJSBFKSSDGFO-IIHALWDASA-N
• SMILES: CC(=CC1=CC(=C(C=C1)OC2C(C(C(O2)C(=O)C)O)O)O)C(=O)NC3C(C(C4C(C3O)OCO4)O)O

Hygromycin A is a Borrelia burgdorferi-selective antibiotic. Hygromycin A is a spirochete-specific antibacterial that is conducive to gut health. Hygromycin A can be used for Lyme disease research[1].
Hygromycin A selectively kills Borrelia burgdorferi and has a favorable impact on the gut microbiota composition, leading to eubiosis[1].

Reference

[1]. Arnaboldi PM, et al. Hygromycin A in the Lymelight. Cell Host Microbe. 2021 Nov 10;29(11):1599-1601.
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