Hyoscyamine Sulfate

• CAT Number: M014712
• CAS Number: 6835-16-1
• Molecular Formula: C34H52N2O12S
• Molecular Weight: 712.852
• Purity: ≥95%
• Synonyms: [3(S)-ENDO]-8-METHYL-8-AZABICYCLO[3.2.1]OCT-3-YL ESTER, ALPHA-(HYDROXYMETHYL)-BENZENEACETIC ACID SULFATE DIHYDRATE;HYOSCYAMINE SULFATE DIHYDRATE;HYOSCYAMINE SULPHATE;HYOSCYAMINE SULFATE;BENZENEACETIC ACID, ALPHA-(HYDROXYMETHYL)-, 8-METHYL-8-AZABICYCL
• Storage: -20°C
• IUPAC Name: [(1R,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] (2S)-3-hydroxy-2-phenylpropanoate;sulfuric acid;dihydrate
• InChI: InChI=1S/2C17H23NO3.H2O4S.2H2O/c2*1-18-13-7-8-14(18)10-15(9-13)21-17(20)16(11-19)12-5-3-2-4-6-12;1-5(2,3)4;;/h2*2-6,13-16,19H,7-11H2,1H3;(H2,1,2,3,4);2*1H2/t2*13-,14+,15?,16-;;;/m11.../s1
• InChIKey: BXSVDJUWKSRQMD-OMLVBYQESA-N
• SMILES: CN1C2CCC1CC(C2)OC(=O)C(CO)C3=CC=CC=C3.CN1C2CCC1CC(C2)OC(=O)C(CO)C3=CC=CC=C3.O.O.OS(=O)(=O)O

Hyoscyamine Sulfate(cas 6835-16-1) is the sulfate salt of a belladonna alkaloid derivative and the levorotatory form of racemic atropine isolated from the plants Hyoscyamus niger or Atropa belladonna, which exhibits anticholinergic activity. 

Reference

1: Jones JB, Dula DJ. The efficacy of sublingual hyoscyamine sulfate and
intravenous ketorolac tromethamine in the relief of ureteral colic. Am J Emerg
Med. 1998 Oct;16(6):557-9. PubMed PMID: 9786536.

2: Myers JH, Moro-Sutherland D, Shook JE. Anticholinergic poisoning in colicky
infants treated with hyoscyamine sulfate. Am J Emerg Med. 1997 Sep;15(5):532-5.
PubMed PMID: 9270398.

3: Werner G. [Studies on the metabolism of tropane alkaloids. V. Enzymatic
preparation of (+)-hyoscyamine-sulfate–H2O]. Arzneimittelforschung. 1967
Nov;17(11):1467. German. PubMed PMID: 5632273.