I-XW-053

• CAT Number: I012546
• CAS Number: 5496-35-5
• Molecular Formula: C22H16N2O2
• Molecular Weight: 340.38
• Purity: ≥95%
• Synonyms: 4-(4,5-Diphenyl-1H-imidazol-2-yl)-benzoic acid
• IUPAC Name: 4-(4,5-diphenyl-1H-imidazol-2-yl)benzoic acid
• InChI: InChI=1S/C22H16N2O2/c25-22(26)18-13-11-17(12-14-18)21-23-19(15-7-3-1-4-8-15)20(24-21)16-9-5-2-6-10-16/h1-14H,(H,23,24)(H,25,26)
• InChIKey: BCXPNUSETAZHEQ-UHFFFAOYSA-N
• SMILES: C1=CC=C(C=C1)C2=C(N=C(N2)C3=CC=C(C=C3)C(=O)O)C4=CC=CC=C4

I-XW-053（Cat No.:I012546）is a selective small molecule inhibitor targeting the enzyme soluble epoxide hydrolase (sEH). sEH plays a role in the metabolism of epoxy fatty acids, which are involved in various physiological processes, including inflammation, blood pressure regulation, and tissue repair. By inhibiting sEH, I-XW-053 aims to increase the levels of beneficial epoxy fatty acids, potentially reducing inflammation, improving vascular function, and providing therapeutic effects in cardiovascular and metabolic diseases. Preclinical studies suggest its potential in managing conditions like hypertension, diabetes, and chronic inflammation, although further clinical trials are needed to confirm its efficacy and safety.