For research use only. Not for therapeutic Use.
I942 is a first in class, selective non-cyclic nucleotide (NCN) EPAC1 agonist. I942 can attenuate proinflammatory cytokine signalling normally associated with cardiovascular diseases[1].
| Catalog Number | I029015 |
| CAS Number | 868145-09-9 |
| Synonyms | N-(2,4-dimethylphenyl)sulfonyl-2-naphthalen-2-yloxyacetamide |
| Molecular Formula | C20H19NO4S |
| Purity | ≥95% |
| InChI | InChI=1S/C20H19NO4S/c1-14-7-10-19(15(2)11-14)26(23,24)21-20(22)13-25-18-9-8-16-5-3-4-6-17(16)12-18/h3-12H,13H2,1-2H3,(H,21,22) |
| InChIKey | KCRXXSQZEZOCFM-UHFFFAOYSA-N |
| SMILES | CC1=CC(=C(C=C1)S(=O)(=O)NC(=O)COC2=CC3=CC=CC=C3C=C2)C |
| Reference | [1]. Graeme Barker, et al. The Potential of a Novel Class of EPAC-Selective Agonists to Combat Cardiovascular Inflammation. J Cardiovasc Dev Dis. 2017 Dec 5;4(4):22. |
