For research use only. Not for therapeutic Use.
IACS-8968 (S-enantiomer) is the S-enantiomer of IACS-8968. IACS-8968 is a dual IDO and TDO inhibitor, with pIC50s of 6.43 for IDO and <5 for TDO, respectively.
| Catalog Number | I019889 |
| CAS Number | 2239305-70-3 |
| Synonyms | (5S)-6,6-dimethyl-8-[7-(trifluoromethyl)imidazo[1,5-a]pyridin-5-yl]-1,3,8-triazaspiro[4.5]decane-2,4-dione |
| Molecular Formula | C17H18F3N5O2 |
| Purity | ≥95% |
| InChI | InChI=1S/C17H18F3N5O2/c1-15(2)8-24(4-3-16(15)13(26)22-14(27)23-16)12-6-10(17(18,19)20)5-11-7-21-9-25(11)12/h5-7,9H,3-4,8H2,1-2H3,(H2,22,23,26,27)/t16-/m1/s1 |
| InChIKey | UBMTZODMRPHSBC-MRXNPFEDSA-N |
| SMILES | CC1(CN(CCC12C(=O)NC(=O)N2)C3=CC(=CC4=CN=CN34)C(F)(F)F)C |
| Reference | [1]. ARYL SULFONOHYDRAZIDES. WO 2017189386 A1. |
