Iadademstat (ORY-1001) 2HCl

• CAT Number: I001655
• CAS Number: 1431326-61-2
• Molecular Formula: C15H22N2 . 2HCl
• Molecular Weight: 303.27
• Purity: ≥95%
• Storage: 3 years-20°Cpowder
• SMILES: C1CC(CCC1N)NC2CC2C3=CC=CC=C3.Cl.Cl

ORY-1001 (RG-6016) 2HCl is an orally active and selective lysine-specific demethylase LSD1/KDM1A inhibitor with IC50 of <20 nM, with high selectivity against related FAD dependent aminoxidases. Phase 1.

Reference

[1] Maes T, et al. J Clin Oncol. 2013, 31, suppl; abstr. e13543.
[2] Zhang X, et al. FASEB J. 2022 Jan;36(1):e22122.