Ibotenic acid

• CAT Number: I010186
• CAS Number: 2552-55-8
• Molecular Formula: C5H6N2O4
• Molecular Weight: 158.113
• Purity: ≥95%
• Synonyms: α-Amino-(3-hydroxy-5-isoxazolyl)acetic acid
• Target: iGluR
• Solubility: Soluble to 10 mM in water and to 100 mM in 1.1eq. NaOH
• Storage: Desiccate at -20C
• IUPAC Name: 2-amino-2-(3-oxo-1,2-oxazol-5-yl)acetic acid
• InChI: InChI=1S/C5H6N2O4/c6-4(5(9)10)2-1-3(8)7-11-2/h1,4H,6H2,(H,7,8)(H,9,10)
• InChIKey: IRJCBFDCFXCWGO-UHFFFAOYSA-N
• SMILES: C1=C(ONC1=O)C(C(=O)O)N

Ibotenic acid(CAT: I010186) is a potent agonist of both NMDA (N-methyl-D-aspartate) receptors and metabotropic glutamate receptors. It acts as an excitatory neurotransmitter in the central nervous system, affecting synaptic transmission and neuronal signaling. Due to its ability to activate NMDA receptors, ibotenic acid has been used in research to study the mechanisms of excitatory neurotransmission and neurodegenerative diseases. It is derived from the Amanita muscaria mushroom and has hallucinogenic properties. Ibotenic acid has also been investigated for its potential therapeutic applications in certain neurological conditions.