Ibrutinib-biotin

• CAT Number: I002031
• CAS Number: 1599432-18-4
• Molecular Formula: C56H80N12O9S
• Molecular Weight: 1097.37
• Purity: ≥95%
• Target: Btk
• Solubility: 10 mM in DMSO
• Storage: Desiccate at -20C

Ibrutinib-biotin (Cat.No:I002031) is a bioconjugate compound that combines the kinase inhibitor ibrutinib with a biotin moiety. This conjugate allows for targeted delivery of ibrutinib to cells expressing biotin receptors, potentially enhancing its therapeutic efficacy. Ibrutinib-biotin has been explored as a strategy to improve the selectivity and effectiveness of ibrutinib-based therapies.

Reference

[1]. Betty Y. CHANG, et al. Companion diagnostics for tec family kinase inhibitor therapy. WO 2014059368 A1.