For research use only. Not for therapeutic Use.
ICG-carboxylic acid is near-infrared (NIR) fluorescent probe. ICG is a fluorescent dye used in medical diagnostics. ICG has absorption peaking at 800 nm and can absorb the near IR laser energy and release heat in the dyed tissue[1][2].
Indocyanine green (ICG) is a water-soluble compound that is widely and safely used in medical diagnostics for its well-established fluorescence properties. It has been used in fluorescence-guided surgery to identify critical structures, including intra-abdominal tumors[1].
| Catalog Number | I044730 |
| CAS Number | 181934-09-8 |
| Synonyms | 6-[2-[(1E,3E,5E,7Z)-7-[1,1-dimethyl-3-(4-sulfobutyl)benzo[e]indol-2-ylidene]hepta-1,3,5-trienyl]-1,1-dimethylbenzo[e]indol-3-ium-3-yl]hexanoate |
| Molecular Formula | C45H50N2O5S |
| Purity | ≥95% |
| InChI | InChI=1S/C45H50N2O5S/c1-44(2)39(46(30-16-8-11-25-41(48)49)37-28-26-33-19-12-14-21-35(33)42(37)44)23-9-6-5-7-10-24-40-45(3,4)43-36-22-15-13-20-34(36)27-29-38(43)47(40)31-17-18-32-53(50,51)52/h5-7,9-10,12-15,19-24,26-29H,8,11,16-18,25,30-32H2,1-4H3,(H-,48,49,50,51,52) |
| InChIKey | HIBVKROMGIHYKL-UHFFFAOYSA-N |
| SMILES | CC1(C(=[N+](C2=C1C3=CC=CC=C3C=C2)CCCCCC(=O)[O-])C=CC=CC=CC=C4C(C5=C(N4CCCCS(=O)(=O)O)C=CC6=CC=CC=C65)(C)C)C |
| Reference | [1]. Taylor JS, et al. Combined application of Indocyanine green (ICG) and laser lead to targeted tumor cell destruction. J Pediatr Surg. 2018;53(12):2475-2479. [2]. Mačianskienė R, et al. Spectral characteristics of voltage-sensitive indocyanine green fluorescence in the heart. Sci Rep. 2017;7(1):7983. Published 2017 Aug 11. |
