ICI 118,551 hydrochloride

• CAT Number: I011852
• CAS Number: 72795-19-8
• Molecular Formula: C17H28ClNO2
• Molecular Weight: 313.87
• Purity: ≥95%
• Synonyms: ICI-118551 HCl
• Storage: 20°C
• Related CAS: 91021-57-7; 72795-01-8
• IUPAC Name: (2R,3S)-1-[(7-methyl-2,3-dihydro-1H-inden-4-yl)oxy]-3-(propan-2-ylamino)butan-2-ol
• InChI: InChI=1S/C17H27NO2/c1-11(2)18-13(4)16(19)10-20-17-9-8-12(3)14-6-5-7-15(14)17/h8-9,11,13,16,18-19H,5-7,10H2,1-4H3/t13-,16-/m0/s1
• InChIKey: VFIDUCMKNJIJTO-BBRMVZONSA-N
• SMILES: CC1=C2CCCC2=C(C=C1)OC[C@@H]([C@H](C)NC(C)C)O

ICI 118,551 Hydrochloride（Cat No.:I011852）is a selective beta-2 adrenergic receptor antagonist widely used in pharmacological research. By specifically blocking beta-2 receptors, it inhibits the actions of endogenous catecholamines like adrenaline and noradrenaline on smooth muscles, particularly in the lungs, vascular system, and uterus. ICI 118,551 Hydrochloride is valuable in studying the role of beta-2 receptors in conditions such as asthma, cardiovascular diseases, and metabolic disorders. Its selectivity allows researchers to differentiate between the effects mediated by beta-2 receptors and those of other adrenergic receptor subtypes, aiding in drug development and mechanistic studies.