ICI-164384

For research use only. Not for therapeutic Use.

  • CAT Number: I029086
  • CAS Number: 98007-99-9
  • Molecular Formula: C34H55NO3
  • Molecular Weight: 525.82
  • Purity: 98%
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ICI-164384 is an estrogen antagonist.


Catalog Number I029086
CAS Number 98007-99-9
Synonyms

ICI 164384; ICI164384; ICI-164384; ICIM164384; ICI-M164384; ICI M164384

Molecular Formula C34H55NO3
Purity 98%
Solubility To be determined
Appearance Solid powder
Storage Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
IUPAC Name Estra-1,3,5(10)-triene-7-undecanamide, N-butyl-3,17-dihydroxy-N-methyl-, (7alpha,17beta)-
InChI InChI=1S/C34H55NO3/c1-4-5-22-35(3)32(38)15-13-11-9-7-6-8-10-12-14-25-23-26-24-27(36)16-17-28(26)29-20-21-34(2)30(33(25)29)18-19-31(34)37/h16-17,24-25,29-31,33,36-37H,4-15,18-23H2,1-3H3/t25-,29-,30+,31+,33-,34+/m1/s1
InChIKey BVVFOLSZMQVDKV-KXQIQQEYSA-N
SMILES CCCCN(C)C(=O)CCCCCCCCCC[C@@H]1Cc2cc(O)ccc2[C@H]3CC[C@]4(C)[C@@H](O)CC[C@H]4[C@H]13
Reference

1. Nicholson RI, Gee JM, Manning DL, Wakeling AE, Montano MM, Katzenellenbogen BS. Responses to pure antiestrogens (ICI 164384, ICI 182780) in estrogen-sensitive and -resistant experimental and clinical breast cancer. Ann N Y Acad Sci. 1995 Jun 12;761:148-63. doi: 10.1111/j.1749-6632.1995.tb31376.x. PMID: 7625718.
2. Coradini D, Biffi A, Pirronello E, Di Fronzo G. The effect of ICI 164384 and beta-interferon on the growth and steroid receptor profile of breast cancer cell lines. Anticancer Res. 1995 Nov-Dec;15(6B):2557-61. PMID: 8669823.

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