For research use only. Not for therapeutic Use.
IDFP (Cat No.: R044064) is an organophosphorus compound that has a dual inhibitory effect on MAGL and FAAH with IC50 values of 0.8 and 3 nM, respectively. at 10 mg/kg, IDFP increased brain levels of 2-AG and AEA by more than 10-fold and decreased levels of arachidonic acid by a similar magnitude.
| Catalog Number | R044064 |
| CAS Number | 615250-02-7 |
| Synonyms | Isopropyl Dodecylfluorophosphonate |
| Molecular Formula | C15H32FO2P |
| Purity | ≥95% |
| Target | Neuronal Signaling |
| Storage | -20°C |
| IUPAC Name | 1-[fluoro(propan-2-yloxy)phosphoryl]dodecane |
| InChI | InChI=1S/C15H32FO2P/c1-4-5-6-7-8-9-10-11-12-13-14-19(16,17)18-15(2)3/h15H,4-14H2,1-3H3 |
| InChIKey | SFRALHFBKRAJPW-UHFFFAOYSA-N |
| SMILES | CCCCCCCCCCCCP(=O)(OC(C)C)F |
| Reference | 1.Nomura, D.K.,Blankman, J.L.,Simon, G.M., et al. Activation of the endocannabinoid system by organophosphorus nerve agents. Nature Chemical Biology 4(6), 373-378 (2008). |
