For research use only. Not for therapeutic Use.
IDO-IN-6 (NLG-1486) is an indoleamine 2,3-dioxygenase (IDO) inhibitor extracted from patent WO WO2012142237A1, Compound 1486, has an IC50 of <1 μM.
IDO-IN-6 (Compound 1486) is an indoleamine 2,3-dioxygenase (IDO) inhibitor with an IC50 of <1 μM (this is the concentration of IDO-IN-6 at which inhibits 50% of enzymatic activity using recombinant human IDO)[1].
| Catalog Number | I001541 |
| CAS Number | 1402837-76-6 |
| Synonyms | 4-[(1S)-2-[(5S)-6-fluoro-5H-imidazo[5,1-a]isoindol-5-yl]-1-hydroxyethyl]cyclohexan-1-ol |
| Molecular Formula | C18H21FN2O2 |
| Purity | ≥95% |
| InChI | InChI=1S/C18H21FN2O2/c19-14-3-1-2-13-16-9-20-10-21(16)15(18(13)14)8-17(23)11-4-6-12(22)7-5-11/h1-3,9-12,15,17,22-23H,4-8H2/t11?,12?,15-,17-/m0/s1 |
| InChIKey | YGACXVRLDHEXKY-VDPJLGHJSA-N |
| SMILES | C1CC(CCC1C(CC2C3=C(C=CC=C3F)C4=CN=CN24)O)O |
| Reference | [1]. Mautino, et al. Preparation of fused imidazole derivatives as IDO inhibitors. From PCT Int. Appl. (2012), 20121018. |
