IEM-1460

• CAT Number: I010436
• CAS Number: 121034-89-7
• Molecular Formula: C19H38Br2N2
• Molecular Weight: 454.33
• Purity: ≥95%
• Synonyms: 5-(1-adamantylmethylamino)pentyl-trimethylazanium;bromide;hydrobromide
• InChI: InChI=1S/C19H37N2.2BrH/c1-21(2,3)8-6-4-5-7-20-15-19-12-16-9-17(13-19)11-18(10-16)14-19;;/h16-18,20H,4-15H2,1-3H3;2*1H/q+1;;/p-1
• InChIKey: CQTDZUSQSTUZDA-UHFFFAOYSA-M
• SMILES: C[N+](C)(C)CCCCCNCC12CC3CC(C1)CC(C3)C2.Br.[Br-]

IEM-1460 blocks both AMPA and NMDA glutamate receptor with anticonvulsant effect in vivo[1].

Reference

[1]. Schlesinger F, et al. Two mechanisms of action of the adamantane derivative IEM-1460 at human AMPA-type glutamate receptors. Br J Pharmacol. 2005 Jul;145(5):656-63.
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