For research use only. Not for therapeutic Use.
IGF-I (24-41) (Insulin-like Growth Factor I (24-41)) is amino acids 24 to 41 fragment of IGF-I. IGF-I, a 70 aa polypeptide hormone, is a trophic factor for both neurons and glial cells. IGF-I is partly responsible for systemic growth hormone (GH) activities. IGF-I has anabolic, antioxidant, anti-inflammatory and cytoprotective actions. IGF-I (24-41) regulates somatic growth and behavioral development[1][2][3].
IGF-I (24-41) (ICV; 200 ng dose; 2 µL; postnatal days 2, 4, and 7) regulates somatic growth and behavioral development[2].
| Catalog Number | M106900 |
| CAS Number | 135861-49-3 |
| Molecular Formula | C88H133N27O28 |
| Purity | ≥95% |
| Reference | [1]. Puche JE, et al. Human conditions of insulin-like growth factor-I (IGF-I) deficiency. J Transl Med. 2012 Nov 14;10:224. [2]. D Santucci, et al. IGF-I and IGF-I24-41 but not IGF-I57-70 affect somatic and neurobehavioral development of newborn male mice. Brain Res Bull. 1994;35(4):367-71. [3]. Dan Meng, et al. Insulin-like growth factor-I (IGF-I) induces epidermal growth factor receptor transactivation and cell proliferation through reactive oxygen species. Free Radic Biol Med. 2007 Jun 1;42(11):1651-60. |
