For research use only. Not for therapeutic Use.
IHVR-11029 is a small molecule inhibitor of ER α-glucosidases, with an EC50 of 0.09 μM[1].
IHVR-11029 exhibits EC50 values of 1.3 μM, 3.3 μM and 0.75 μM for BVDV, TARV and DENV, respectively.
| Catalog Number | I006906 |
| CAS Number | 1383152-30-4 |
| Synonyms | (2R,3R,4R,5S)-1-[6-(2,5-difluorophenoxy)hexyl]-2-(hydroxymethyl)piperidine-3,4,5-triol |
| Molecular Formula | C18H27F2NO5 |
| Purity | ≥95% |
| InChI | InChI=1S/C18H27F2NO5/c19-12-5-6-13(20)16(9-12)26-8-4-2-1-3-7-21-10-15(23)18(25)17(24)14(21)11-22/h5-6,9,14-15,17-18,22-25H,1-4,7-8,10-11H2/t14-,15+,17-,18-/m1/s1 |
| InChIKey | XGCVJVFPIXDHPA-CYGHRXIMSA-N |
| SMILES | C1C(C(C(C(N1CCCCCCOC2=C(C=CC(=C2)F)F)CO)O)O)O |
| Reference | [1]. Jinhong Chang, et al. Small molecule inhibitors of ER α-glucosidases are active against multiple hemorrhagic fever viruses. Antiviral Res. 2013 Jun;98(3):432-40. |
