IKKε-IN-1

• CAT Number: I001127
• CAS Number: 1292310-49-6
• Molecular Formula: C26H27N5O3
• Molecular Weight: 457.52
• Purity: ≥95%
• Synonyms: 5-(2-((4-morpholinophenyl)amino)pyrimidin-4-yl)-2-((tetrahydro-2H-pyran-4-yl)oxy)benzonitrile
• Target: IκB/IKK
• Solubility: DMSO: ≤ 21.5 mg/mL
• Storage: Store at -20°C
• IUPAC Name: 5-[2-(4-morpholin-4-ylanilino)pyrimidin-4-yl]-2-(oxan-4-yloxy)benzonitrile
• InChI: InChI=1S/C26H27N5O3/c27-18-20-17-19(1-6-25(20)34-23-8-13-32-14-9-23)24-7-10-28-26(30-24)29-21-2-4-22(5-3-21)31-11-15-33-16-12-31/h1-7,10,17,23H,8-9,11-16H2,(H,28,29,30)
• InChIKey: BWABTWGSXHTHCG-UHFFFAOYSA-N
• SMILES: C1COCCC1OC2=C(C=C(C=C2)C3=NC(=NC=C3)NC4=CC=C(C=C4)N5CCOCC5)C#N

TBK1/IKKε-IN-2 (Cat No.:I001127), also known as Ikk epsilon-in-1, IKKε-IN-1, MDK10496, is a dual inhibitor of TBK1 and IKKε. If you need, please contact us in time, and we will reply to you as soon as possible within 24 hours.

Reference

[1]. Preparation of amino-pyrimidine compounds as inhibitors of TBK1 kinase and IKK kinase epsilon. From PCT Int. Appl. (2011), WO 2011046970 A1 20110421.