For research use only. Not for therapeutic Use.
IL-2-IN-1 is a potent IL-2 inhibitor with an IC50 value of 1978 nM. IL-2-IN-1 shows antiproliferative activities[1].
IL-2-IN-1 (compound 2) shows antiproliferative activities with IC50s of 340, 1266 nM for human PBMC and rat PBMC, respectively[1].
| Catalog Number | I043348 |
| CAS Number | 245747-10-8 |
| Synonyms | N-[4-[3,5-bis(trifluoromethyl)pyrazol-1-yl]phenyl]-3,5-dimethyl-1,2-oxazole-4-carboxamide |
| Molecular Formula | C17H12F6N4O2 |
| Purity | ≥95% |
| InChI | InChI=1S/C17H12F6N4O2/c1-8-14(9(2)29-26-8)15(28)24-10-3-5-11(6-4-10)27-13(17(21,22)23)7-12(25-27)16(18,19)20/h3-7H,1-2H3,(H,24,28) |
| InChIKey | LAHVQXKWWOOVLX-UHFFFAOYSA-N |
| SMILES | CC1=C(C(=NO1)C)C(=O)NC2=CC=C(C=C2)N3C(=CC(=N3)C(F)(F)F)C(F)(F)F |
| Reference | [1]. Djuric SW, et al. 3,5-Bis(trifluoromethyl)pyrazoles: a novel class of NFAT transcription factor regulator. J Med Chem. 2000 Aug 10;43(16):2975-81. |
