Immethridine dihydrobromide

• CAT Number: I010539
• CAS Number: 699020-93-4
• Molecular Formula: C9H11Br2N3
• Molecular Weight: 321.02
• Purity: ≥95%
• Synonyms: 4-(1H-Imidazol-4-ylmethyl)pyridine dihydrobromide
• Target: Neuronal Signaling
• Solubility: Soluble to 100 mM in water
• Storage: Desiccate at RT
• IUPAC Name: 4-(1H-imidazol-5-ylmethyl)pyridine;dihydrobromide
• InChI: InChI=1S/C9H9N3.2BrH/c1-3-10-4-2-8(1)5-9-6-11-7-12-9;;/h1-4,6-7H,5H2,(H,11,12);2*1H
• InChIKey: CYNKWHIKNDIVDR-UHFFFAOYSA-N
• SMILES: C1=CN=CC=C1CC2=CN=CN2.Br.Br

Immethridine dihydrobromide(CAT: I010539) is a highly selective and potent histamine H3 receptor (H3R) antagonist. By blocking H3 receptors, it inhibits the autoregulatory feedback mechanism that controls the release of histamine and other neurotransmitters such as acetylcholine, dopamine, and norepinephrine. This action enhances neurotransmitter release, making Immethridine dihydrobromide a valuable tool in neurological and cognitive research. It is primarily used to investigate potential treatments for neurodegenerative disorders, cognitive impairments, and conditions like Alzheimer’s disease and narcolepsy, where histaminergic dysregulation plays a significant role.