For research use only. Not for therapeutic Use.
IMP2-IN-1 (compound 4) is a potent IMP2 inhibitor with IC50 value of 81.3~127.5 for IMP2 RNA sequence. IMP2-IN-1 reduces IMP2 in SW480 cells. IMP2-IN-1 significantly reduces the viability of both differentiated and non-differentiated Huh7 cells[1].
| Catalog Number | I043565 |
| CAS Number | 1480482-51-6 |
| Synonyms | 2-[(4-phenylbenzoyl)amino]-5-(trifluoromethoxy)benzoic acid |
| Molecular Formula | C21H14F3NO4 |
| Purity | ≥95% |
| InChI | InChI=1S/C21H14F3NO4/c22-21(23,24)29-16-10-11-18(17(12-16)20(27)28)25-19(26)15-8-6-14(7-9-15)13-4-2-1-3-5-13/h1-12H,(H,25,26)(H,27,28) |
| InChIKey | ACJZUAUURQGKNK-UHFFFAOYSA-N |
| SMILES | C1=CC=C(C=C1)C2=CC=C(C=C2)C(=O)NC3=C(C=C(C=C3)OC(F)(F)F)C(=O)O |
| Reference | [1]. Dahlem C, et al. First Small-Molecule Inhibitors Targeting the RNA-Binding Protein IGF2BP2/IMP2 for Cancer Therapy. ACS Chem Biol. 2022;17(2):361-375. |
