IN04

For research use only. Not for therapeutic Use.

  • CAT Number: I029292
  • Molecular Formula: C20H19N3O6S
  • Molecular Weight: 429.447
  • Purity: 98%
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IN04 is a Novel inhibitor of LRRK1, suppressing osteoclast function, but not osteoclast differentiation.


Catalog Number I029292
Synonyms

IN04; IN-04; IN 04

Molecular Formula C20H19N3O6S
Purity 98%
Solubility Soluble in DMSO
Appearance Solid powder
Storage Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
IUPAC Name Methyl 3-(2-((5-(3,5-dimethoxyphenyl)-1,3,4-oxadiazol-2-yl)thio)acetamido)benzoate
InChI InChI=1S/C20H19N3O6S/c1-26-15-8-13(9-16(10-15)27-2)18-22-23-20(29-18)30-11-17(24)21-14-6-4-5-12(7-14)19(25)28-3/h4-10H,11H2,1-3H3,(H,21,24)
InChIKey MCQJCSNFOKHYLJ-UHFFFAOYSA-N
SMILES O=C(OC)C1=CC=CC(NC(CSC2=NN=C(C3=CC(OC)=CC(OC)=C3)O2)=O)=C1
Reference

1: Si M, Zeng C, Goodluck H, Shen S, Mohan S, Xing W. A small molecular inhibitor
of LRRK1 identified by homology modeling and virtual screening suppresses
osteoclast function, but not osteoclast differentiation, in vitro. Aging (Albany
NY). 2019 May 21;11(10):3250-3261. doi: 10.18632/aging.101977. PubMed PMID:
31113907; PubMed Central PMCID: PMC6555463.

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