Indeloxazine

• CAT Number: I029328
• CAS Number: 60929-23-9
• Molecular Formula: C14H17NO2
• Molecular Weight: 231.29
• Purity: 98%
• Synonyms: Indeloxazine
• Solubility: To be determined
• Appearance: Solid powder
• Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
• IUPAC Name: Morpholine, 2-((1H-inden-7-yloxy)methyl)-
• InChI: InChI=1S/C14H17NO2/c1-3-11-4-2-6-14(13(11)5-1)17-10-12-9-15-7-8-16-12/h1-4,6,12,15H,5,7-10H2
• InChIKey: MADRVGBADLFHMO-UHFFFAOYSA-N
• SMILES: C(Oc1cccc2C=CCc12)C3CNCCO3

Indeloxazine (Cat.No:I029328) is a nootropic drug primarily used in Japan for the treatment of cerebrovascular disorders and cognitive impairments. It exerts its effects through multiple mechanisms, including enhancing cerebral blood flow, increasing dopamine and serotonin levels, and protecting neurons from oxidative stress. Indeloxazine shows potential in improving cognitive function and has been investigated for various neurological conditions.

Reference

1. Shimizu-Sasamata M, Yamamoto M, Harada M. Cerebral activating properties of indeloxazine HCl and its optical isomers. Pharmacol Biochem Behav. 1993 Jun;45(2):335-41. doi: 10.1016/0091-3057(93)90248-r. PMID: 8327539.
2. Yamamoto M, Kawabata S, Shimizu M. Pharmacological effects of indeloxazine, a new cerebral activator, on brain functions distinct from other cerebral metabolic enhancers. Neuropharmacology. 1989 Dec;28(12):1291-7. doi: 10.1016/0028-3908(89)90001-4. PMID: 2615913.