For research use only. Not for therapeutic Use.
Indolelactic acid-d5 is the deuterium labeled Indolelactic acid. Indolelactic acid is a tryptophan (Trp) catabolite in Azotobacter vinelandii cultures.
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
| Catalog Number | I045600 |
| CAS Number | 2470130-19-7 |
| Synonyms | 2-hydroxy-3-(2,4,5,6,7-pentadeuterio-1H-indol-3-yl)propanoic acid |
| Molecular Formula | C11H6D5NO3 |
| Purity | ≥95% |
| InChI | InChI=1S/C11H11NO3/c13-10(11(14)15)5-7-6-12-9-4-2-1-3-8(7)9/h1-4,6,10,12-13H,5H2,(H,14,15)/i1D,2D,3D,4D,6D |
| InChIKey | XGILAAMKEQUXLS-SNOLXCFTSA-N |
| SMILES | C1=CC=C2C(=C1)C(=CN2)CC(C(=O)O)O |
| Reference | [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Francisco García-Tabares, et al. Production of 3-indoleacetic acid and 3-indolelactic acid in Azotobacter vinelandii cultures supplemented with tryptophan. Appl Microbiol Biotechnol.1987 Mar, 25 (6):502–506. |
