Indolmycin

• CAT Number: R005170
• CAS Number: 21200-24-8
• Molecular Formula: C14H15N3O2
• Molecular Weight: 257.29
• Purity: ≥95%
• Synonyms: 5S-[(1R)-1-(1H-indol-3-yl)ethyl]-2-(methylamino)-4(5H)-oxazolone
• Target: Antibiotic
• Solubility: Soluble in ethanol, methanol, DMF or DMSO. Poor water solubility.
• Storage: -20°C
• IUPAC Name: (5S)-5-[(1R)-1-(1H-indol-3-yl)ethyl]-2-methylimino-1,3-oxazolidin-4-one
• InChI: InChI=1S/C14H15N3O2/c1-8(12-13(18)17-14(15-2)19-12)10-7-16-11-6-4-3-5-9(10)11/h3-8,12,16H,1-2H3,(H,15,17,18)/t8-,12+/m1/s1
• InChIKey: GNTVWGDQPXCYBV-PELKAZGASA-N
• SMILES: C[C@@H]([C@H]1C(=O)NC(=NC)O1)C2=CNC3=CC=CC=C32

Indolmycin（Cat No.:R005170）is a natural antibiotic derived from Streptomyces species, known for its specific inhibition of bacterial tryptophanyl-tRNA synthetase. By interfering with protein synthesis, it exhibits antibacterial activity, particularly against Gram-positive bacteria and certain Gram-negative pathogens, including Helicobacter pylori. Indolmycin’s unique mechanism of action and selective targeting make it a valuable tool in antimicrobial research and drug development. Its potential as an antibiotic alternative in combating resistant bacterial strains highlights its significance in addressing the global challenge of antibiotic resistance and advancing therapeutic strategies.