Indomethacin

• CAT Number: A000306
• CAS Number: 53-86-1
• Molecular Formula: C19H16ClNO4
• Molecular Weight: 357.80
• Purity: ≥95%
• Synonyms: Indometacin; 53-86-1; Indocin; Indomethacine; Indometacine
• Target: COX
• Solubility: Soluble in DMSO > 10 mM
• Storage: -20°C
• IUPAC Name: 2-[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetic acid
• InChI: InChI=1S/C19H16ClNO4/c1-11-15(10-18(22)23)16-9-14(25-2)7-8-17(16)21(11)19(24)12-3-5-13(20)6-4-12/h3-9H,10H2,1-2H3,(H,22,23)
• InChIKey: CGIGDMFJXJATDK-UHFFFAOYSA-N
• SMILES: CC1=C(C2=C(N1C(=O)C3=CC=C(C=C3)Cl)C=CC(=C2)OC)CC(=O)O

Indomethacin（Cat No.:A000306）is a potent nonsteroidal anti-inflammatory drug (NSAID) used to treat pain, inflammation, and fever associated with various conditions like arthritis, gout, and bursitis. It works by inhibiting cyclooxygenase (COX) enzymes, reducing the production of prostaglandins that cause inflammation and pain. Indomethacin is effective in managing acute flare-ups of chronic conditions and is also used to close patent ductus arteriosus in premature infants. Available in oral, rectal, and injectable forms, it provides versatile relief, making it a valuable option for managing inflammatory and pain-related disorders.