Indomethacin heptyl ester

• CAT Number: I011553
• CAS Number: 282728-47-6
• Molecular Formula: C26H30ClNO4
• Molecular Weight: 456.00
• Purity: ≥95%
• Synonyms: 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic acid, 1-heptyl ester
• Target: COX
• Solubility: Soluble in DMSO
• Storage: Store at -20°C
• IUPAC Name: heptyl 2-[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetate
• InChI: InChI=1S/C26H30ClNO4/c1-4-5-6-7-8-15-32-25(29)17-22-18(2)28(24-14-13-21(31-3)16-23(22)24)26(30)19-9-11-20(27)12-10-19/h9-14,16H,4-8,15,17H2,1-3H3
• InChIKey: PYBCHCVNKGZCOH-UHFFFAOYSA-N
• SMILES: CCCCCCCOC(=O)CC1=C(N(C2=C1C=C(C=C2)OC)C(=O)C3=CC=C(C=C3)Cl)C

Indomethacin heptyl ester（Cat No.:I011553）is a lipid-soluble derivative of indomethacin, a nonsteroidal anti-inflammatory drug (NSAID) used to reduce inflammation, pain, and fever. The heptyl ester modification enhances its bioavailability and ability to cross cell membranes more easily than the parent drug. Indomethacin works by inhibiting cyclooxygenase (COX) enzymes, which are involved in the production of prostaglandins—compounds responsible for inflammation and pain. Preclinical studies suggest that the heptyl ester form may improve the pharmacokinetics and tissue penetration of indomethacin, offering a potential advantage in treating chronic inflammation and related conditions with fewer side effects.