Indospicine HCl

• CAT Number: I029353
• CAS Number: 16377-01-8
• Molecular Formula: C7H16ClN3O2
• Molecular Weight: 209.67
• Purity: 98%
• Synonyms: Indospicine HCl; Indospicine hydrochloride
• Solubility: To be determined
• Appearance: Solid powder
• Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
• IUPAC Name: Heptanoic acid, 2,7-diamino-7-imino-, monohydrochloride, (S)- (9CI)
• InChI: InChI=1S/C7H15N3O2.ClH/c8-5(7(11)12)3-1-2-4-6(9)10;/h5H,1-4,8H2,(H3,9,10)(H,11,12);1H/t5-;/m0./s1
• InChIKey: QDHZACJZLQSYAP-JEDNCBNOSA-N
• SMILES: Cl.N[C@@H](CCCCC(=N)N)C(=O)O

Indospicine HCl is a toxin which causes hepatotoxicosis.

Reference

1. Sultan S, Osborne SA, Addepalli R, Netzel G, Netzel ME, Fletcher MT. Indospicine cytotoxicity and transport in human cell lines. Food Chem. 2018 Nov 30;267:119-123. doi: 10.1016/j.foodchem.2017.08.029. Epub 2017 Aug 8. PMID: 29934145.
2. Shuvayeva GY, Bobak YP, Vovk OI, Kunz-Schughart LA, Fletcher MT, Stasyk OV. Indospicine combined with arginine deprivation triggers cancer cell death via caspase-dependent apoptosis. Cell Biol Int. 2021 Mar;45(3):518-527. doi: 10.1002/cbin.11321. Epub 2020 Mar 12. PMID: 32068315.