For research use only. Not for therapeutic Use.
Indospicine hydrochloride（Cat No.:I029353）is a synthetic derivative of the naturally occurring compound indospicine, which is an amino acid found in certain plants, notably in the genus Indigofera. It acts as an inhibitor of protein synthesis by interfering with the aminoacylation process in cells. Indospicine has been studied for its potential cytotoxic effects on certain cancer cells, particularly in the context of its ability to modulate immune responses. Its use in research includes investigating cancer therapy and immune modulation. However, due to its toxicity, it is not used clinically and remains under investigation for various potential applications in biomedicine.
| Catalog Number | I029353 |
| CAS Number | 16377-01-8 |
| Synonyms | Indospicine HCl; Indospicine hydrochloride |
| Molecular Formula | C7H16ClN3O2 |
| Purity | 98% |
| Solubility | To be determined |
| Appearance | Solid powder |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| IUPAC Name | (2S)-2,7-diamino-7-iminoheptanoic acid;hydrochloride |
| InChI | InChI=1S/C7H15N3O2.ClH/c8-5(7(11)12)3-1-2-4-6(9)10;/h5H,1-4,8H2,(H3,9,10)(H,11,12);1H/t5-;/m0./s1 |
| InChIKey | QDHZACJZLQSYAP-JEDNCBNOSA-N |
| SMILES | C(CCC(=N)N)C[C@@H](C(=O)O)N.Cl |
| Reference | 1. Sultan S, Osborne SA, Addepalli R, Netzel G, Netzel ME, Fletcher MT. Indospicine cytotoxicity and transport in human cell lines. Food Chem. 2018 Nov 30;267:119-123. doi: 10.1016/j.foodchem.2017.08.029. Epub 2017 Aug 8. PMID: 29934145. |
