For research use only. Not for therapeutic Use.
Ingenol-3-palmitate, an ingenane diterpenoid, is a nature product that could be isolated from the roots of Euphorbia ebracteolata. Ingenol-3-palmitate is a potent HIV-1 (HIV) inhibitor with an IC50 value of 4.1 nM[1].
| Catalog Number | R010316 |
| CAS Number | 52557-26-3 |
| Synonyms | [(1S,4S,5S,6R,9R,10R,12R,14R)-5,6-dihydroxy-7-(hydroxymethyl)-3,11,11,14-tetramethyl-15-oxo-4-tetracyclo[7.5.1.01,5.010,12]pentadeca-2,7-dienyl] hexadecanoate |
| Molecular Formula | C36H58O6 |
| Purity | ≥95% |
| InChI | InChI=1S/C36H58O6/c1-6-7-8-9-10-11-12-13-14-15-16-17-18-19-29(38)42-33-24(2)22-35-25(3)20-28-30(34(28,4)5)27(32(35)40)21-26(23-37)31(39)36(33,35)41/h21-22,25,27-28,30-31,33,37,39,41H,6-20,23H2,1-5H3/t25-,27-,28-,30+,31-,33+,35+,36+/m1/s1 |
| InChIKey | DOSPRDHNGNPKKJ-IYPSJCSWSA-N |
| SMILES | CCCCCCCCCCCCCCCC(=O)OC1C(=CC23C1(C(C(=CC(C2=O)C4C(C4(C)C)CC3C)CO)O)O)C |
| Reference | [1]. Huang YS, et, al. Potent Anti-HIV Ingenane Diterpenoids from Euphorbia ebracteolata. J Nat Prod. 2019 Jun 28;82(6):1587-1592. |
