For research use only. Not for therapeutic Use.
Ingliforib is a potent glucokinase inhibitor used in diabetes research to regulate glucose metabolism. By inhibiting glucokinase, a key enzyme involved in glucose uptake and conversion in the liver and pancreas, Ingliforib helps reduce glucose production and lower blood sugar levels. This compound is primarily studied for its potential to treat type 2 diabetes by addressing hyperglycemia through non-insulin-dependent pathways. Ingliforib’s mechanism of action makes it a valuable tool for exploring new therapeutic strategies aimed at improving glycemic control and managing metabolic disorders.
| Catalog Number | I007337 |
| CAS Number | 186392-65-4 |
| Synonyms | 5-chloro-N-[(2S,3R)-4-[(3R,4S)-3,4-dihydroxypyrrolidin-1-yl]-3-hydroxy-4-oxo-1-phenylbutan-2-yl]-1H-indole-2-carboxamide |
| Molecular Formula | C23H24ClN3O5 |
| Purity | ≥95% |
| InChI | InChI=1S/C23H24ClN3O5/c24-15-6-7-16-14(9-15)10-18(25-16)22(31)26-17(8-13-4-2-1-3-5-13)21(30)23(32)27-11-19(28)20(29)12-27/h1-7,9-10,17,19-21,25,28-30H,8,11-12H2,(H,26,31)/t17-,19-,20+,21+/m0/s1 |
| InChIKey | GVDRRZOORHCTAN-MJUUVYJYSA-N |
| SMILES | C1C(C(CN1C(=O)C(C(CC2=CC=CC=C2)NC(=O)C3=CC4=C(N3)C=CC(=C4)Cl)O)O)O |
