Inosine (dI) phosphoramidite

For research use only. Not for therapeutic Use.

  • CAT Number: I029379
  • CAS Number: 141684-35-7
  • Molecular Formula: C40H47N6O7P
  • Molecular Weight: 754.81
  • Purity: 98%
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Inosine (dI) phosphoramidite(Cat No.:I029379), is a chemical compound used in nucleic acid synthesis. It is a phosphoramidite derivative of inosine, a nucleoside found in RNA molecules. Inosine (dI) phosphoramidite is utilized as a building block during solid-phase DNA and RNA synthesis, enabling the incorporation of inosine residues into the oligonucleotide sequence. This modification can provide altered base-pairing properties and enhance the stability and functionality of the synthesized nucleic acids for various biological and biomedical applications, including diagnostics, therapeutics, and research.


Catalog Number I029379
CAS Number 141684-35-7
Synonyms

Inosine (dI) phosphoramidite

Molecular Formula C40H47N6O7P
Purity 98%
Target DNA/RNA Synthesis
Solubility Soluble in DMSO
Appearance Solid powder
Storage -20°C
IUPAC Name 3-[[(2R,3S,5R)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-5-(6-oxo-1H-purin-9-yl)oxolan-3-yl]oxy-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile
InChI InChI=1S/C40H47N6O7P/c1-27(2)46(28(3)4)54(51-22-10-21-41)53-34-23-36(45-26-44-37-38(45)42-25-43-39(37)47)52-35(34)24-50-40(29-11-8-7-9-12-29,30-13-17-32(48-5)18-14-30)31-15-19-33(49-6)20-16-31/h7-9,11-20,25-28,34-36H,10,22-24H2,1-6H3,(H,42,43,47)/t34-,35+,36+,54?/m0/s1
InChIKey ZKGZROFWRPJVEB-XZYUMQGLSA-N
SMILES CC(C)N(C(C)C)P(OCCC#N)OC1CC(OC1COC(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)C4=CC=C(C=C4)OC)N5C=NC6=C5N=CNC6=O

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