For research use only. Not for therapeutic Use.
Inosine (dI) phosphoramidite(Cat No.:I029379), is a chemical compound used in nucleic acid synthesis. It is a phosphoramidite derivative of inosine, a nucleoside found in RNA molecules. Inosine (dI) phosphoramidite is utilized as a building block during solid-phase DNA and RNA synthesis, enabling the incorporation of inosine residues into the oligonucleotide sequence. This modification can provide altered base-pairing properties and enhance the stability and functionality of the synthesized nucleic acids for various biological and biomedical applications, including diagnostics, therapeutics, and research.
Catalog Number | I029379 |
CAS Number | 141684-35-7 |
Synonyms | Inosine (dI) phosphoramidite |
Molecular Formula | C40H47N6O7P |
Purity | 98% |
Target | DNA/RNA Synthesis |
Solubility | Soluble in DMSO |
Appearance | Solid powder |
Storage | -20°C |
IUPAC Name | 3-[[(2R,3S,5R)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-5-(6-oxo-1H-purin-9-yl)oxolan-3-yl]oxy-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile |
InChI | InChI=1S/C40H47N6O7P/c1-27(2)46(28(3)4)54(51-22-10-21-41)53-34-23-36(45-26-44-37-38(45)42-25-43-39(37)47)52-35(34)24-50-40(29-11-8-7-9-12-29,30-13-17-32(48-5)18-14-30)31-15-19-33(49-6)20-16-31/h7-9,11-20,25-28,34-36H,10,22-24H2,1-6H3,(H,42,43,47)/t34-,35+,36+,54?/m0/s1 |
InChIKey | ZKGZROFWRPJVEB-XZYUMQGLSA-N |
SMILES | CC(C)N(C(C)C)P(OCCC#N)OC1CC(OC1COC(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)C4=CC=C(C=C4)OC)N5C=NC6=C5N=CNC6=O |