Inosine

• CAT Number: I004195
• CAS Number: 58-63-9
• Molecular Formula: C10H12N4O5
• Molecular Weight: 268.23
• Purity: ≥95%
• Target: GPCR/G Protein
• Solubility: DMSO ≥ 9.7 mg/mL
• Storage: Room Temperature
• IUPAC Name: 9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one
• InChI: InChI=1S/C10H12N4O5/c15-1-4-6(16)7(17)10(19-4)14-3-13-5-8(14)11-2-12-9(5)18/h2-4,6-7,10,15-17H,1H2,(H,11,12,18)/t4-,6-,7-,10-/m1/s1
• InChIKey: UGQMRVRMYYASKQ-KQYNXXCUSA-N
• SMILES: C1=NC2=C(C(=O)N1)N=CN2C3C(C(C(O3)CO)O)O

Inosine（Cat No.:I004195） is a nucleoside compound composed of hypoxanthine and ribose. Participate in energy metabolism and protein synthesis in the body. It can be used to treat leukopenia and thrombocytopenia caused by various reasons.

Reference

[1]. Moore TL et al. Inosine enhances recovery of grasp following cortical injury to the primary motor cortex of the rhesus monkey. Restor Neurol Neurosci. 2016 Aug 1.

[2]. Welihinda AA et al. The adenosine metabolite inosine is a functional agonist of the adenosine A2A receptor with a unique signaling bias. Cell Signal. 2016 Jun;28(6):552-60.

[3]. Junqueira SC et al. Inosine, an Endogenous Purine Nucleoside, Suppresses Immune Responses and Protects Mice from Experimental Autoimmune Encephalomyelitis: a Role for A2A Adenosine Receptor. Mol Neurobiol. 2016 Apr 30.