Inositol 1,4,5-trisphosphate

• CAT Number: R074500
• CAS Number: 85166-31-0
• Molecular Formula: C6-H15-O15-P3
• Molecular Weight: 420.091
• Purity: ≥95%
• InChI: 1S/C6H15O15P3/c7-1-2(8)5(20-23(13,14)15)6(21-24(16,17)18)3(9)4(1)19-22(10,11)12/h1-9H,(H2,10,11,12)(H2,13,14,15)(H2,16,17,18)/t1-,2+,3+,4-,5-,6-/m0/s1
• InChIKey: MMWCIQZXVOZEGG-HOZKJCLWSA-N
• SMILES: P(O[C@@H]1[C@H]([C@@H]([C@H](O)<wbr>[C@@H]([C@H]1O)<wbr>OP(O)<wbr>(O)<wbr>=O)<wbr>O)<wbr>OP(O)<wbr>(O)<wbr>=O)<wbr>(O)<wbr>(O)<wbr>=O

Inositol 1,4,5-trisphosphate (IP3) is a crucial signaling molecule involved in cellular processes, particularly in regulating intracellular calcium levels. Formed by the enzymatic cleavage of phosphatidylinositol 4,5-bisphosphate (PIP2), IP3 binds to receptors on the endoplasmic reticulum, triggering the release of calcium ions into the cytoplasm. This calcium release plays a pivotal role in various physiological functions, including muscle contraction, cell proliferation, and neurotransmission. IP3 is widely studied for its importance in signal transduction pathways and its involvement in many cellular responses.