inotersen

• CAT Number: I048041
• CAS Number: 1492984-65-2
• Molecular Weight: 7183.1
• Purity: ≥95%
• Target: TTR
• Appearance: Solid

Inotersen (brand name Tegsedi) is a medication used to treat polyneuropathy in adults with hereditary transthyretin-mediated amyloidosis (hATTR). This rare genetic condition leads to the accumulation of abnormal amyloid protein deposits in various tissues, including nerves. Inotersen is an antisense oligonucleotide that works by reducing the production of transthyretin, the protein responsible for amyloid formation. By lowering transthyretin levels, inotersen aims to slow the progression of hATTR polyneuropathy, potentially improving symptoms and preserving nerve function.