Iobenguane I 131

• CAT Number: I029404
• CAS Number: 77679-27-7
• Molecular Formula: C8H10131IN3
• Molecular Weight: 279.09
• Purity: 98%
• Synonyms: 3-Iodobenzylguanidine, 131I-MIBG, Azedra, I-131 MIBG, Iobenguane (131I) , Iobenguane I 131, MIBG, MIBG-(131 I), Ultratrace iobenguane I131
• Solubility: Soluble in DMSO
• Appearance: Solid powder
• Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
• IUPAC Name: 2-[(3-(131I)iodanylphenyl)methyl]guanidine
• InChI: InChI=1S/C8H10IN3/c9-7-3-1-2-6(4-7)5-12-8(10)11/h1-4H,5H2,(H4,10,11,12)/i9+4
• InChIKey: PDWUPXJEEYOOTR-JRGAVVOBSA-N
• SMILES: C1=CC(=CC(=C1)[131I])CN=C(N)N

Iobenguane I-131(CAT: I029404) is a radiolabeled norepinephrine analog used in targeted radiotherapy and diagnostic imaging, primarily in oncology research. By selectively binding to adrenergic nerve terminals and tumors expressing norepinephrine transporters, it delivers precise radiation to neuroendocrine tumors such as pheochromocytomas and paragangliomas. This mechanism facilitates both therapeutic efficacy and imaging clarity, aiding in the study of tumor behavior and treatment response. With its dual diagnostic and therapeutic utility, Iobenguane I-131 is an indispensable tool for advancing research in targeted radiopharmaceutical development and neuroendocrine oncology.