Ionizable lipid-1 (compound II-10) is an ionizable lipid (pKa=6.16) that can be used to prepare lipid nanoparticles (LNP) with bilayer structure[1].
| Catalog Number | I040870 |
| CAS Number | 2055939-68-7 |
| Synonyms | ditridecan-7-yl 10-[3-(dimethylamino)propyl-octanoylamino]nonadecanedioate |
| Molecular Formula | C58H114N2O5 |
| Purity | ≥95% |
| InChI | InChI=1S/C58H114N2O5/c1-8-13-18-27-38-48-56(61)60(52-41-51-59(6)7)53(42-32-28-23-25-30-39-49-57(62)64-54(44-34-19-14-9-2)45-35-20-15-10-3)43-33-29-24-26-31-40-50-58(63)65-55(46-36-21-16-11-4)47-37-22-17-12-5/h53-55H,8-52H2,1-7H3 |
| InChIKey | VBFYPCGDFUFVCZ-UHFFFAOYSA-N |
| SMILES | CCCCCCCC(=O)N(CCCN(C)C)C(CCCCCCCCC(=O)OC(CCCCCC)CCCCCC)CCCCCCCCC(=O)OC(CCCCCC)CCCCCC |
| Reference | [1]. Thomas D Madden, et al. Lamellar lipid nanoparticles. Patent WO2019089828A1. |
