Ionomycin Calcium

• CAT Number: R014600
• CAS Number: 56092-82-1
• Molecular Formula: C41H70O9 • Ca
• Molecular Weight: 747.07
• Purity: ≥95%
• Synonyms: Calcium Ionomycin; (4R,6S,8S,10Z,12R,14R,16E,18R,19R,20S,21S)-11,19,21-Trihydroxy-4,6,8,12,14,18,20-heptamethyl-22-[(2S,2’R,5S,5’S)-octahydro-5’-[(1R)-1-hydroxyethyl]-2,5’-dimethyl[2,2’-bifuran]-5-yl]-9-oxo-10,16-Docosadienoic Acid Calcium Salt
• Target: Neuronal Signaling
• Solubility: Soluble in DMSO > 10 mM
• Storage: Desiccate at -20 ℃
• IUPAC Name: calcium;(4R,6S,8S,10Z,12R,14R,16E,18R,19R,20S,21S)-19,21-dihydroxy-22-[(2S,5S)-5-[(2R,5S)-5-[(1R)-1-hydroxyethyl]-5-methyloxolan-2-yl]-5-methyloxolan-2-yl]-4,6,8,12,14,18,20-heptamethyl-11-oxido-9-oxodocosa-10,16-dienoate
• InChI: 1S/C41H72O9.Ca/c1-25(21-29(5)34(43)24-35(44)30(6)22-27(3)20-26(2)14-15-38(46)47)12-11-13-28(4)39(48)31(7)36(45)23-33-16-18-41(10,49-33)37-17-19-40(9,50-37)32(8)42;/h11,13,24-33,36-37,39,42-43,45,48H,12,14-23H2,1-10H3,(H,46,47);/q;+2/p-2/b13-11+,34-24-;/t25-,26-,27+,28-,29-,30+,31+,32-,33+,36+,37-,39-,40+,41+;/m1./s1
• InChIKey: WKRWUYKLUMMAKG-WYGBAUISSA-L
• SMILES: C[C@H](CCC(=O)[O-])C[C@H](C)C[C@H](C)C(=O)/C=C(/[C@H](C)C[C@H](C)C/C=C/[C@@H](C)[C@H]([C@@H](C)[C@H](C[C@@H]1CC[C@@](O1)(C)[C@H]2CC[C@@](O2)(C)[C@@H](C)O)O)O)\[O-].[Ca+2]

Ionomycin Calcium is a calcium ionophore derived from Streptomyces conglobatus, widely used in research to increase intracellular calcium levels by facilitating the transport of Ca²⁺ across cellular membranes. It is a valuable tool for studying calcium-dependent processes such as signal transduction, T-cell activation, and apoptosis. Ionomycin is commonly used in immunological studies to stimulate cytokine production, such as interleukin-2 (IL-2), and in assays for intracellular calcium measurement. Its precision in modulating calcium flux makes it essential for cell biology and pharmacological research.