Iopamidol

• CAT Number: A000093
• CAS Number: 60166-93-0
• Molecular Formula: C17H22I3N3O8
• Molecular Weight: 777.09
• Purity: ≥95%
• Synonyms: Iopamiro, Isovue, Iopamiron, Niopam, Solutrast
• Storage: Store at -20°C
• InChI: 1S/C17H22I3N3O8/c1-6(28)15(29)23-14-12(19)9(16(30)21-7(2-24)3-25)11(18)10(13(14)20)17(31)22-8(4-26)5-27/h6-8,24-28H,2-5H2,1H3,(H,21,30)(H,22,31)(H,23,29)/t6-/m0/s1
• InChIKey: XQZXYNRDCRIARQ-LURJTMIESA-N
• SMILES: CC(C(=O)NC1=C(C(=C(C(=C1I)C(=O)NC(CO)CO)I)C(=O)NC(CO)CO)I)O

Iopamidol, also known as Gastromiro and SQ-13396, is a non-ionic, water-soluble contrast agent which is used in myelography, arthrography, nephroangiography, arteriography, and other radiological procedures.

Reference

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chemical exchange saturation transfer (CEST) MRI approach for mapping renal pH
using iopamidol. Magn Reson Med. 2017 Jul 7. doi: 10.1002/mrm.26817. [Epub ahead
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2: Rogers D, Sheth C, Eisenmenger L, Mignogna E, Winter T. Iopamidol as an oral
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3: Tian FX, Xu B, Lin YL, Hu CY, Zhang TY, Xia SJ, Chu WH, Gao NY.
Chlor(am)ination of iopamidol: Kinetics, pathways and disinfection by-products
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5: Hu J, Dong H, Qu J, Qiang Z. Enhanced degradation of iopamidol by
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7: Rosenberg C, Martínez-Rodrigo JJ, Lonjedo Vicent E, Macho J, Lim L, Todoran
TM; Peripheral Discomfort Study Investigator Panel. Randomized, Double-Blind
Study Comparing Patient Comfort and Safety Between Iodixanol 320 mg I/mL and
Iopamidol 370 mg I/mL in Patients Undergoing Peripheral Arteriography – The
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8: Borrelli MP, Setacci F, de Donato G, Galzerano G, Benevento D, Mele M,
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9: Matsushita T, Hashizuka M, Kuriyama T, Matsui Y, Shirasaki N. Use of
orbitrap-MS/MS and QSAR analyses to estimate mutagenic transformation products of
iopamidol generated during ozonation and chlorination. Chemosphere. 2016
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10: Moon BF, Jones KM, Chen LQ, Liu P, Randtke EA, Howison CM, Pagel MD. A
comparison of iopromide and iopamidol, two acidoCEST MRI contrast media that
measure tumor extracellular pH. Contrast Media Mol Imaging. 2015
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