Ipfencarbazone

• CAT Number: I002635
• CAS Number: 212201-70-2
• Molecular Formula: C18H14Cl2F2N4O2
• Molecular Weight: 427.23
• Purity: ≥95%
• Solubility: 10 mM in DMSO
• Storage: Store at -20°C
• InChI: InChI=1S/C18H14Cl2F2N4O2/c1-10(2)25(16-6-4-12(21)8-14(16)22)17(27)24-9-23-26(18(24)28)15-5-3-11(19)7-13(15)20/h3-10H,1-2H3
• InChIKey: DHYXNIKICPUXJI-UHFFFAOYSA-N
• SMILES: CC(C)N(C1=C(C=C(C=C1)F)F)C(=O)N2C=NN(C2=O)C3=C(C=C(C=C3)Cl)Cl

Ipfencarbazone (CAT: I002635) is a herbicide agent that is currently under development for the control of weeds, specifically watergrass, in rice crops. It belongs to the class of chemical compounds known as pyrimidinyloxybenzoates. Ipfencarbazone works by inhibiting an enzyme called acetolactate synthase, which is involved in the synthesis of essential branched-chain amino acids in plants. By disrupting this enzymatic pathway, ipfencarbazone effectively inhibits the growth and development of targeted weeds, helping to improve crop yield and quality in rice cultivation.

Reference

1. Shokuhin Eiseigaku Zasshi. 2015;56(5):205-10. doi: 10.3358/shokueishi.56.205.

[Development of Determination Method of Ipfencarbazone in Agricultural Products,
Livestock Products and Seafood by LC-MS/MS].

Imai K(1), Onoue K, Ishii R, Takano M, Nemoto S, Teshima R.

Author information:
(1)Saitama Prefectural Institute of Public Health.

A method for the determination of ipfencarbazone in agricultural products,
livestock products and seafood by LC-MS/MS was developed. Agricultural samples
were extracted with acetone. An aliquot of crude extract was partitioned with
n-hexane and sat. sodium chloride solution. Clean-up was performed using GC/PSA
and C18 cartridges. In the case of livestock products and seafood, samples were
extracted with a mixture of acetone and n-hexane, and the organic layer was
collected. After acetonitrile-hexane partitioning, the extract was cleaned up
using PAS and C18 cartridges. The gradient LC separation was performed on a C18
column with acetonitrile-water containing acetic acid as a mobile phase, and MS
with positive ion electrospray ionization was used for detection. The average
recoveries (n=5) of ipfencarbazone from 16 kinds of agricultural products,
livestock products and seafood spiked at the MRLs or at the uniform limits (0.01
ppm) were 73-101%, and the relative standard deviations were 1.3-5.1%. The limit
of quantitation of the developed method was 0.01 mg/kg for ipfencarbazone.