For research use only. Not for therapeutic Use.
IQDMA(CAT: I029486) is a selective inhibitor of the transcription factor STAT5, a key regulator of cell proliferation, survival, and differentiation. By targeting STAT5, IQDMA disrupts its activity in signaling pathways such as JAK/STAT, which are often dysregulated in cancers and immune-related disorders. This makes it particularly valuable in oncology and immunology research, where it aids in exploring therapeutic strategies for conditions like leukemia, lymphoma, and autoimmune diseases. Its specificity for STAT5 provides a targeted approach to studying the molecular mechanisms underlying these diseases and developing novel treatments aimed at modulating transcription factor activity.
| CAS Number | 401463-02-3 |
| Synonyms | C524250; IQDMA cpd; IQDMA |
| Molecular Formula | C19H20N4 |
| Purity | 98% |
| Solubility | Soluble in DMSO |
| Appearance | Solid powder |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| IUPAC Name | N-(11H-indolo[3,2-c]quinolin-6-yl)-N',N'-dimethylethane-1,2-diamine |
| InChI | InChI=1S/C19H20N4/c1-23(2)12-11-20-19-17-13-7-3-5-9-15(13)21-18(17)14-8-4-6-10-16(14)22-19/h3-10,21H,11-12H2,1-2H3,(H,20,22) |
| InChIKey | UROLFQZUYMCOHV-UHFFFAOYSA-N |
| SMILES | CN(C)CCNC1=NC2=CC=CC=C2C3=C1C4=C(N3)C=CC=C4 |
