For research use only. Not for therapeutic Use.
IR-806 is a near-infrared cyanine liquid crystal dye. IR-806 can be used as a molecular antenna to synthesized nanoprobes (NPs). IR-806 can be used for in vivo imaging studies[1][2].
IR-806 (0.1 mg) and folic acid (0.02 mg) were activated with EDC/NHS (1×10−4 mol) in DMSO (10 mL) solution. After 30 mins, the PL-PEG-NH2 coated UCN solution (containing UCNs 5 mg) was added and stirred at room temperature for 4 hrs. The reaction product was purified by centrifugation at 10,000 rpm for 5 mins and suspended in 5 mL of DMSO, obtained upconversion nanocrystals (UCNs) for the preparation of nanoprobes[2].
| Catalog Number | I042351 |
| Synonyms | sodium;4-[(2Z)-2-[(2E)-2-[2-chloro-3-[(E)-2-[3,3-dimethyl-1-(4-sulfonatobutyl)indol-1-ium-2-yl]ethenyl]cyclopent-2-en-1-ylidene]ethylidene]-3,3-dimethylindol-1-yl]butane-1-sulfonate |
| Molecular Formula | C37H44ClN2NaO6S2 |
| Purity | ≥95% |
| InChI | InChI=1S/C37H45ClN2O6S2.Na/c1-36(2)29-13-5-7-15-31(29)39(23-9-11-25-47(41,42)43)33(36)21-19-27-17-18-28(35(27)38)20-22-34-37(3,4)30-14-6-8-16-32(30)40(34)24-10-12-26-48(44,45)46;/h5-8,13-16,19-22H,9-12,17-18,23-26H2,1-4H3,(H-,41,42,43,44,45,46);/q;+1/p-1 |
| InChIKey | MIOUAELAUIYKFC-UHFFFAOYSA-M |
| SMILES | CC1(C2=CC=CC=C2[N+](=C1C=CC3=C(C(=CC=C4C(C5=CC=CC=C5N4CCCCS(=O)(=O)[O-])(C)C)CC3)Cl)CCCCS(=O)(=O)[O-])C.[Na+] |
| Reference | [1]. Zhang YF, et al. Multiple hybridized resonances of IR-806 chromonic molecules strongly coupled to Au nanorods. Nanoscale. 2015 May 14;7(18):8503-9. [2]. Wei Y, et al. Molecular Antenna-Sensitized Upconversion Nanoparticle for Temperature Monitored Precision Photothermal Therapy. Int J Nanomedicine. 2020 Mar 2;15:1409-1420. |
