Irbesartan

• CAT Number: A000217
• CAS Number: 138402-11-6
• Molecular Formula: C25H28N6O
• Molecular Weight: 428.50
• Purity: ≥95%
• Synonyms: 138402-11-6; Aprovel; Avapro; Karvea; SR-47436
• Target: Apoptosis
• Solubility: >17.4mg/mL in DMSO
• Storage: -20°C
• IUPAC Name: 2-butyl-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]-1,3-diazaspiro[4.4]non-1-en-4-one
• InChI: InChI=1S/C25H28N6O/c1-2-3-10-22-26-25(15-6-7-16-25)24(32)31(22)17-18-11-13-19(14-12-18)20-8-4-5-9-21(20)23-27-29-30-28-23/h4-5,8-9,11-14H,2-3,6-7,10,15-17H2,1H3,(H,27,28,29,30)
• InChIKey: YOSHYTLCDANDAN-UHFFFAOYSA-N
• SMILES: CCCCC1=NC2(CCCC2)C(=O)N1CC3=CC=C(C=C3)C4=CC=CC=C4C5=NNN=N5

Irbesartan（Cat No.:A000217）is an angiotensin II receptor blocker (ARB) used to treat hypertension and manage kidney disease in patients with type 2 diabetes. It works by blocking the effects of angiotensin II, a hormone that constricts blood vessels, thus helping to lower blood pressure and improve blood flow. Irbesartan is effective in reducing the risk of stroke, heart attack, and progression of diabetic nephropathy. Its once-daily dosing and favorable side effect profile make it a commonly prescribed option for long-term cardiovascular and renal protection.

Reference

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