Irbesartan-d7

• CAT Number: M072180
• CAS Number: 1329496-43-6
• Molecular Formula: C25H28N6O
• Molecular Weight: 435.583
• Purity: ≥95%
• Storage: -20°C
• IUPAC Name: 2-(2,2,3,3,4,4,4-heptadeuteriobutyl)-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]-1,3-diazaspiro[4.4]non-1-en-4-one
• InChI: InChI=1S/C25H28N6O/c1-2-3-10-22-26-25(15-6-7-16-25)24(32)31(22)17-18-11-13-19(14-12-18)20-8-4-5-9-21(20)23-27-29-30-28-23/h4-5,8-9,11-14H,2-3,6-7,10,15-17H2,1H3,(H,27,28,29,30)/i1D3,2D2,3D2
• InChIKey: YOSHYTLCDANDAN-NCKGIQLSSA-N
• SMILES: [2H]C([2H])([2H])C([2H])([2H])C([2H])([2H])CC1=NC2(CCCC2)C(=O)N1CC3=CC=C(C=C3)C4=CC=CC=C4C5=NNN=N5

Irbesartan-d7 is a deuterated form of Irbesartan, labeled with seven deuterium atoms. This high-purity isotopically labeled compound is crucial for research in pharmacology, particularly in the study of angiotensin II receptor blockers (ARBs) used to treat hypertension and related cardiovascular conditions. It is extensively used in mass spectrometry and other analytical techniques to investigate the pharmacokinetics, metabolism, and bioavailability of Irbesartan in biological systems. The deuterium labeling provides enhanced accuracy and sensitivity in analytical measurements, making Irbesartan-d7 an essential tool for researchers focused on optimizing antihypertensive therapies and understanding the detailed metabolic pathways of ARBs.