For research use only. Not for therapeutic Use.
Iseganan is an anti-microbial peptide that is active against both Gram-positive and Gram-negative bacteria and fungi. Iseganan kills a broad-spectrum of bacteria and fungi by attaching to and destroying the integrity of the lipid cell membranes. Iseganan can be used for oral mucositis research[1][2][3].
Iseganan (200 and 400 μg/mL; 24 h) disrupts T. crassiceps cysticerci in vitro[3].
Iseganan (intraperitoneal injection; 200 and 400 μg per mouse; once) shows anti-parasite activity in T. crassiceps murine cysticercosis model[3].
| Catalog Number | I042735 |
| CAS Number | 257277-05-7 |
| Molecular Formula | C78H126N30O18S4 |
| Purity | ≥95% |
| Reference | [1]. Toney JH. Iseganan (IntraBiotics pharmaceuticals). Curr Opin Investig Drugs. 2002 Feb;3(2):225-8. [2]. Giles FJ, et al. Iseganan HCl: a novel antimicrobial agent. Expert Opin Investig Drugs. 2002 Aug;11(8):1161-70. [3]. Landa A, et al. Antimicrobial peptides (Temporin A and Iseganan IB-367): effect on the cysticerci of Taenia crassiceps. Mol Biochem Parasitol. 2009 Apr;164(2):126-30. |
