Isoalantolactone

• CAT Number: I003628
• CAS Number: 470-17-7
• Molecular Formula: C15H20O2
• Molecular Weight: 232.32
• Purity: ≥95%
• Solubility: 10 mM in DMSO
• Storage: Store at -20C

Isoalantolactone(CAT: I003628)is a natural compound derived from plants of the Asteraceae family. It possesses a variety of pharmacological activities and has been extensively studied for its potential therapeutic applications. Isoalantolactone exhibits anti-inflammatory, anticancer, antimicrobial, antiparasitic, and antioxidant properties. It has been shown to inhibit the growth of cancer cells, induce apoptosis, and inhibit inflammatory pathways. Isoalantolactone also demonstrates antimicrobial activity against various pathogens, including bacteria and fungi. Furthermore, it has been investigated for its potential in treating parasitic infections, such as malaria. Isoalantolactone’s diverse pharmacological properties make it a promising compound for further research and development in the field of natural product-based therapeutics.

Reference

[1]. Di W, et al.
Isoalantolactone inhibits constitutive NF-κB activation and induces reactive oxygen species-mediated apoptosis in osteosarcoma U2OS cells through mitochondrial dysfunction. Oncology Reports [2014, 32(4):1585-1593]

[2]. Hong Cai, et al. Growth Inhibition Effects of Isoalantolactone on K562/A02 Cells: Caspase-dependent Apoptotic Pathways, S Phase Arrest, and Downregulation of Bcr/Abl. Phytotherapy Research
Volume 28, Issue 11, pages 1679–1686, November 2014

[3]. Luszczki J. J., et al. Alantolactone and isoalantolactone suppress maximal electroshock-induced tonic seizures in mice. Journal of Pre-Clinical and Clinical Research, 2014; 8(1): 9–12