Isoflupredone 21-Phosphate Ester Disodium Salt

• CAT Number: C001118
• CAS Number: 94088-00-3
• Molecular Formula: C₂₁H₂₆FNa₂O₈P
• Molecular Weight: 502.38
• Purity: ≥95%
• Synonyms: (11β)-9-Fluoro-11,17-dihydroxy-21-(phosphonooxy)-pregna-1,4-diene-3,20-dione Disodium Salt
• Solubility: Methanol (Slightly), Ethanol (Slightly, Sonicated), Water (Slightly)
• Appearance: Whhite to Off-White Solid
• Storage: -20°C, Hygroscopic
• IUPAC Name: disodium;[2-[(8S,9R,10S,11S,13S,14S,17R)-9-fluoro-11,17-dihydroxy-10,13-dimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] phosphate
• InChI: InChI=1S/C21H28FO8P.2Na/c1-18-7-5-13(23)9-12(18)3-4-15-14-6-8-20(26,17(25)11-30-31(27,28)29)19(14,2)10-16(24)21(15,18)22;;/h5,7,9,14-16,24,26H,3-4,6,8,10-11H2,1-2H3,(H2,27,28,29);;/q;2*+1/p-2/t14-,15-,16-,18-,19-,20-,21-;;/m0../s1
• InChIKey: RJCHGSGXNBHMRH-VJVYSMTMSA-L
• SMILES: C[C@]12C[C@@H]([C@]3([C@H]([C@@H]1CC[C@@]2(C(=O)COP(=O)([O-])[O-])O)CCC4=CC(=O)C=C[C@@]43C)F)O.[Na+].[Na+]

Isoflupredone 21-phosphate ester disodium salt（Cat No.:C001118）is a corticosteroid compound used primarily for its anti-inflammatory and immunosuppressive properties. It is a derivative of isoflupredone, which is a synthetic glucocorticoid. The phosphate ester form enhances its solubility and stability, making it suitable for intravenous or intramuscular administration. Isoflupredone 21-phosphate ester disodium salt is used in veterinary medicine, particularly in the treatment of inflammatory conditions in animals such as arthritis, respiratory issues, and other inflammatory disorders. It helps reduce swelling, pain, and immune response. As with other corticosteroids, its use is monitored for potential side effects like immune suppression and gastrointestinal issues.

Reference

Ferrante, M.G., et al.: Anal. Profiles Drug Subs., 6, 43 (1977), Li, A., et al.: Chem. Biol. Interact., 142, 7 (2002), Cruz-Monteagudo, M., et al.: Eur. J. Med. Chem., 40, 1030 (2005),