Isoflupredone 21-Phosphate Ester Disodium Salt

• CAT Number: C001118
• CAS Number: 94088-00-3
• Molecular Formula: C₂₁H₂₆FNa₂O₈P
• Molecular Weight: 502.38
• Purity: ≥95%
• Synonyms: (11β)-9-Fluoro-11,17-dihydroxy-21-(phosphonooxy)-pregna-1,4-diene-3,20-dione Disodium Salt
• Solubility: Methanol (Slightly), Ethanol (Slightly, Sonicated), Water (Slightly)
• Appearance: Whhite to Off-White Solid
• Storage: -20°C, Hygroscopic
• IUPAC Name: disodium;[2-[(8S,9R,10S,11S,13S,14S,17R)-9-fluoro-11,17-dihydroxy-10,13-dimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] phosphate
• InChI: InChI=1S/C21H28FO8P.2Na/c1-18-7-5-13(23)9-12(18)3-4-15-14-6-8-20(26,17(25)11-30-31(27,28)29)19(14,2)10-16(24)21(15,18)22;;/h5,7,9,14-16,24,26H,3-4,6,8,10-11H2,1-2H3,(H2,27,28,29);;/q;2*+1/p-2/t14-,15-,16-,18-,19-,20-,21-;;/m0../s1
• InChIKey: RJCHGSGXNBHMRH-VJVYSMTMSA-L
• SMILES: CC12CC(C3(C(C1CCC2(C(=O)COP(=O)([O-])[O-])O)CCC4=CC(=O)C=CC43C)F)O.[Na+].[Na+]

Isoflupredone 21-Phosphate Ester Disodium Salt (Cat No.:C001118) is a synthetic glucocorticoid, a type of corticosteroid hormone. It is a derivative of isoflupredone, modified by the addition of a phosphate ester group. This compound exhibits potent anti-inflammatory and immunosuppressive properties. It is utilized in pharmaceutical research for its potential in treating inflammatory conditions and autoimmune diseases. As a disodium salt, it is formulated for improved solubility and stability.

Reference

Ferrante, M.G., et al.: Anal. Profiles Drug Subs., 6, 43 (1977), Li, A., et al.: Chem. Biol. Interact., 142, 7 (2002), Cruz-Monteagudo, M., et al.: Eur. J. Med. Chem., 40, 1030 (2005),