For research use only. Not for therapeutic Use.
Isoflurane, also known as Forane and Terrell, is a stable, non-explosive inhalation anesthetic, that has been reported to induce caspase-3 activation.
| Catalog Number | R059047 |
| CAS Number | 26675-46-7 |
| Synonyms | 2-Chloro-2-(difluoromethoxy)-1,1,1-trifluoroethane; (±)-Isoflurane; 1-Chloro-2,2,2-trifluoroethyl difluoromethyl Ether; Aerrane; Attane; Compound 469; Difluoromethyl 1-chloro-2,2,2-trifluoroethyl Ether; Forane; Forene; HCFE 235da2; IsoFlo (anesthetic |
| Molecular Formula | C3H2ClF5O |
| Purity | ≥95% |
| Storage | Store at +4C |
| IUPAC Name | 2-chloro-2-(difluoromethoxy)-1,1,1-trifluoroethane |
| InChI | InChI=1S/C3H2ClF5O/c4-1(3(7,8)9)10-2(5)6/h1-2H |
| InChIKey | PIWKPBJCKXDKJR-UHFFFAOYSA-N |
| SMILES | C(C(F)(F)F)(OC(F)F)Cl |
| Reference | </br>1:Minimum Alveolar Concentration and Cardiopulmonary Effects of Isoflurane in Ring-tailed Lemurs (Lemur catta). K Chinnadurai S, A Balko J, V Williams C.J Am Assoc Lab Anim Sci. 2017 May 18. doi: no_doi/1495129915202. [Epub ahead of print] PMID: 28524022 </br>2:Coronary Sinus Isoflurane Concentration in Cardiac Surgery. Ng KT, Alston RP, Just G, McKenzie C.J Cardiothorac Vasc Anesth. 2017 Mar 9. pii: S1053-0770(17)30277-X. doi: 10.1053/j.jvca.2017.03.014. [Epub ahead of print] PMID: 28506542 </br>3:Brief isoflurane anesthesia regulates striatal AKT-GSK3β signaling and ameliorates motor deficits in a rat model of early-stage Parkinson/’s disease. Leikas JV, Kohtala S, Theilmann W, Jalkanen AJ, Forsberg MM, Rantamäki T.J Neurochem. 2017 May 10. doi: 10.1111/jnc.14066. [Epub ahead of print] PMID: 28488766 </br>4:Elamipretide (SS-31) Ameliorates Isoflurane-Induced Long-Term Impairments of Mitochondrial Morphogenesis and Cognition in Developing Rats. Wu J, Hao S, Sun XR, Zhang H, Li H, Zhao H, Ji MH, Yang JJ, Li K.Front Cell Neurosci. 2017 Apr 25;11:119. doi: 10.3389/fncel.2017.00119. eCollection 2017. PMID: 28487636 Free PMC Article</br>5:Effects of Vitamin B12 on postoperative cognitive dysfunction induced by isoflurane anesthesia in rats. Sha HY, Zhao JB, Sha MX, Guo SM.Eur Rev Med Pharmacol Sci. 2017 Apr;21(8):1959-1966. PMID: 28485779 Free Article</br>6:Isoflurane and sevoflurane affects Wnt/β-catenin signaling pathways in hippocampal formation of neonatal rats. Ma JF, Li CG, Sun MY, Shao GF, Li KZ.Eur Rev Med Pharmacol Sci. 2017 Apr;21(8):1980-1989. PMID: 28485776 Free Article</br>7:Neuroprotection provided by isoflurane pre-conditioning and post-conditioning. Jiang M, Sun L, Feng DX, Yu ZQ, Gao R, Sun YZ, Chen G.Med Gas Res. 2017 Mar 30;7(1):48-55. doi: 10.4103/2045-9912.202910. eCollection 2017 Jan-Mar. Review. PMID: 28480032 Free PMC Article</br>8:A comparison of renal responses to sevoflurane and isoflurane in patients undergoing donor nephrectomy: a randomized controlled trial. Ong Sio LCL, Dela Cruz RGC, Bautista AF.Med Gas Res. 2017 Mar 30;7(1):19-27. doi: 10.4103/2045-9912.202906. eCollection 2017 Jan-Mar. PMID: 28480028 Free PMC Article</br>9:Another Example of Comparative Effectiveness: Sevoflurane Versus Isoflurane. Grocott HP.J Cardiothorac Vasc Anesth. 2017 Feb 4. pii: S1053-0770(17)30085-X. doi: 10.1053/j.jvca.2017.02.035. [Epub ahead of print] No abstract available. PMID: 28465121 </br>10:Neuroprotection by plumbagin involves BDNF-TrkB-PI3K/Akt and ERK1/2/JNK pathways in isoflurane-induced neonatal rats. Yuan JH, Pan F, Chen J, Chen CE, Xie DP, Jiang XZ, Guo SJ, Zhou J.J Pharm Pharmacol. 2017 May 2. doi: 10.1111/jphp.12681. [Epub ahead of print] PMID: 28464236 |
