For research use only. Not for therapeutic Use.
Isomaculosidine is an alkaloid that can be isolated from D. dasycarpus. Isomaculosidine can inhibit nitric oxide (NO) production in lipopolysaccharide (LPS)-stimulated BV2 microglial cells[1].
| Catalog Number | R052747 |
| CAS Number | 518-96-7 |
| Synonyms | 6,8-dimethoxy-9-methylfuro[2,3-b]quinolin-4-one |
| Molecular Formula | C14H13NO4 |
| Purity | ≥95% |
| InChI | InChI=1S/C14H13NO4/c1-15-12-10(6-8(17-2)7-11(12)18-3)13(16)9-4-5-19-14(9)15/h4-7H,1-3H3 |
| InChIKey | FXHBKLQQNAGNJN-UHFFFAOYSA-N |
| SMILES | CN1C2=C(C=C(C=C2OC)OC)C(=O)C3=C1OC=C3 |
| Reference | [1]. Jeong Seon Yoon, et al. Inhibitory alkaloids from Dictamnus dasycarpus root barks on lipopolysaccharide-induced nitric oxide production in BV2 cells. J Enzyme Inhib Med Chem. 2012 Aug;27(4):490-4. |
